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Effect of robot-assisted MS-TLIF on electromyography and erythrocyte immunity in patients with lumbar spinal stenosis
Author:Li Cuangfu, Peng Feng, Wu Meiping , Yang Wei, Peng Bo.
keyword:Lumbar spinal stenosis; Minimally invasive access; Foraminal lumbar interbody fusion; Robotics; Erythrocyte immunization; Electromyography.
Objective To observe the effect of robotic assisted minimally invasive lumbar interbody fusion (MIS⁃
TLIF) on electromyography and erythrocyte immunity in patients with lumbar spinal stenosis.Methods From October 2019
to August 2021, 142 patients with lumbar spinal stenosis were selected from the Department of Orthopedics and Traumatolo⁃
gy of the Department of Traditional Chinese Medicine of Enshi Tujia and Miao Autonomous Prefecture Central Hospital.
They were divided into MIS⁃TLIF group and robot group according to random number table, with 71 patients in each group.
MIS⁃TLIF group line MIS⁃TLIF, robot group line robot assisted MIS⁃TLIF. Perioperative indexes, interbody fusion rate, fu⁃
sion time, complications, and erythrocyte immunity before and after surgery [ synergetic tumor erythrocyte rosette rate
(ATER), erythrocyte C3b receptor (RBC⁃C3Br)] , left and right electromyography [ mean power frequency (MPF), integral
electromyography (EMG)] , lumbar function [ Japan Orthopedic Association Lumbar Evaluation Scale (JOA ), intervertebral
space height, and local Cobb angle] were counted.Results The intraoperative blood loss in the robot group was less than
that in the MIS⁃TLIF group, and the accuracy of pedicle screw placement was better than that in the MIS⁃TLIF group
[t(U)/P = 15.884/ < 0.001,2.563/0.010] .The level of ATER and RBC⁃C3Br in the robot group was higher than that in the MIS⁃
TLIF group (t/P = 4.107/ < 0.001,5.965/ < 0.001) 1 day after operation. At 6 months after operation, the left and right MPF,
EMG and JOA scores and intervertebral space height of the two groups were higher than those before operation, and the
local Cobb angle was lower than that before operation (P < 0.01), but there was no statistically significant difference betweenthe two groups (P > 0.05). There was no significant difference in the rate and time of interbody fusion between the twogroups (P>0.05). The total incidence of complications in the robot group was lower than that in the MIS⁃TLIF group2 /P = 4.351/0.037) .Conclusion Robot⁃assisted MIS⁃TLIF can help alleviate the erythrocyte immunosuppression in pa⁃tients with lumbar spinal stenosis, improve the accuracy of pedicle screw placement, reduce the incidence of complications,and improve EMG.
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Aicardi-Goutieres syndrome; two cases and literature review
Author:Jiang 0iong" , Zeng lan, Zhu Hu , Wang 0iyan, luo ZeminSun Chunhua, Zhu Shuyao.
keyword:Aicardi⁃Goutières syndrome; TREX1 gene; RNASEH2C gene; Diagnosis; Treatment
The clinical data of 2 cases of Aicardi⁃Goutières syndrome were reported and the literature was reviewed.
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A case of type ll Gricelli syndrome secondary to hemophagocytic syndrome and literature review
Author:Huang Jiaojiao .Huang Pei, Shi Xiaogi, li Chunsha, u Yanpeng , Mao 0ing , Chen Yan
keyword:Gricelli syndrome type II; Hemophagocytic syndrome; Diagnosis; Treatment
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Research progress of CD19 in acute myeloid leukemia
Author:Bai Huien , Yan Lixiang , lin Xu, Shi Zhexin.
keyword:Acute myeloid leukemia; CD19; Immunophenotype; Prognosis
CD19 antigen, as a B⁃cell lineage marker, is also expressed in some cells of patients with acute myeloid
leukemia, but its prognosis is still controversial. Therefore, this article mainly introduces the expression of CD19 in acute my⁃
eloid leukemia and discusses its prognosis, so as to provide a certain basis for future diagnosis and treatment.
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Research progress in the molecular mechanism of liver fibrosis
Author: Wu Zhihuang" , Shen Yao, Feng Min , Yang Shenghui.
keyword: Liver fibrosis; Hepatic stellate cells; Molecular mechanism
Liver fibrosis is a healing reaction of chronic liver injury caused by viral infection, alcohol, chemicals,
and other factors. It is a key link in the progression of chronic liver diseases to cirrhosis or liver cancer. How to prevent and
reverse liver fibrosis is a hot and difficult topic in current research, and fully understanding and clarifying the pathogenesis
of liver fibrosis is the basis for prevention and treatment. This article focuses on inflammatory response, oxidative stress,
and TGF⁃ β/SMAD signaling pathway and hepatic stellate cell autophagy, with the aim of deeply understanding the molecu⁃
lar mechanism of liver fibrosis and providing guidance for its prevention and treatment.