Exosomes are vesicles secreted by a variety of cells, which contain a variety of substances, such as lipids, proteins, circular RNA(circRNA), long-chain non-coding RNA(lncRNA) and microRNA(miRNA). However, the expression of multiple exosome-derived cyclic RNA in the plasma of patients with gastric cancer is significantly different from that of normal people, which directly or indirectly affects the metabolism, metastasis and prognosis of tumor. Many studies have shown that exocrine-derived cyclic RNA plays an important role in the development and metastasis of gastric cancer. This article focuses on the role of exocrine-derived cyclic RNA in the diagnosis, metastasis and prognosis of gastric cancer.

Gastric carcinoma;                    Exosomes;                    Circular RNA;