Objective To observe the effect of different surgical methods on cervical disc herniation(CDH) and its influence on cervical curvature, adjacent segment degeneration and safety. Methods From June 2019 to June 2022, 60 patients with single-segment CDH were randomly divided into group A and group B with 30 patients in each group. Both groups were treated with anterior cervical discectomy and fusion(ACDF), group A was treated with Zero-P internal fixation, and group B was treated with traditional fusion cage plate internal fixation. The operation efficacy, operation condition, C2～7 cervical curvature, Cobb angle, cervical function(JOA score), pain degree(NRS score) and complication rate of the two groups were compared before and after the operation.Results There was no statistically significant difference in the excellent and good rate of surgical effect between Group A and Group B(96.67% vs. 90.00%,χ²/P=0.268/0.605).The operation time, fluoroscopy times and hospital stay in Group A were less than those in Group B(t/P=3.947/<0.001, 2.744/0.008, 3.310/0.002). The curvature and Cobb angle of C2-7 cervical spine in the two groups were higher than those before operation 3 and 6 months after operation(P<0.001), but="" there="" was="" no="" significant="" difference="" between="" the="" two="" p="">0.05). The JOA score of the two groups at 3 and 6 months after operation was higher than that before operation, and the NRS score was lower than that before operation(P<0.001), but="" there="" was="" no="" statistically="" significant="" difference="" between="" the="" two="" p="">0.05). The incidence of complications in group A was lower than that in group B(6.67% vs. 26.67%,χ²/P=4.320/0.038). Conclusion Zero-P or traditional fusion cage plate internal fixation in ACDF of single-segment CDH patients can achieve good surgical effect, effectively improve the anatomical structure and function of cervical spine, and reduce the degree of pain. Zero-P has obvious advantages in shortening the operation time, promoting the postoperative recovery of patients, and reducing the incidence of complications.

Cervical disc herniation;                    Discectomy and fusion;                    Zero-cut interbody fusion;                    Cervical curvature;                    Adjacent segmental degeneration;                    Therapeutic effect Safety;