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Exploration of the pathogenesis of heart and lung qi deficiency in stable phase of chronic obstructive pulmonary disease
Time:2025-08-25 Source:Hebei Yiling Hospital,High-level TCM Key Disciplines of National Administration of Traditional Chinese Medicine—Luobing Theory Hebei Luoxue Innovation Medical Research Institute State Key Laboratory for Innovation and Transformation of Luobing Theory

Exploration of the pathogenesis of heart and lung qi deficiency in stable phase of chronic obstructive pulmonary disease

  • Jia Zhenhua

  • Hebei Yiling Hospital,High-level TCM Key Disciplines of National Administration of Traditional Chinese Medicine—Luobing Theory

  • Hebei Luoxue Innovation Medical Research Institute

  • State Key Laboratory for Innovation and Transformation of Luobing Theory

Abstract:This article summarizes the historical literature related to traditional Chinese medicine's heart and lungs, and points out that the core of the theory of heart and lungs is the combination of Zong Qi, heart and lungs, Qi and blood, Ying Wei, and Luo Mai; Based on the diagnosis and treatment of pulmonary collateral disease, this study explores the transmission pattern of "Qi Luo-Airway-Blood Luo" in chronic obstructive pulmonary disease, proposes the core pathogenesis of heart lung qi deficiency, and lays a theoretical foundation for the treatment of "Qi tonifying, blood activating, and meridian unblocking" and the early application of drugs in Stable period of chronic obstructive pulmonary disease; The treatment method of "tonifying qi, promoting blood circulation, and unblocking collaterals" intervenes in chronic obstructive pulmonary disease by protecting pulmonary microvascular endothelial cells, achieving the same treatment of heart and lung, further providing modern experimental data support for the pathogenesis of this disease.

Key words:Chronic obstructive pulmonary disease ; Heart and lung qi deficiency ; Zong Qi ; Pulmonary microvascular endothelial cells ; Yiqi Huoxue Tongluo

Funding: Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202206)