he paper reported a case of chronic recurrent multifocal osteomyelitis,and reviewed the related literatures.

The paper reported a case of IgG4 related diseases associated with primary Sjogren 's syndrome,and re-viewed the related literatures.

Primary malignant pericardial mesothelioma is an extremely rare and fatal malignant tumor of the heart and pericardium. Its etiology and pathogenesis are unknown. The clinical manifestations and imaging examinations of patients often have no obvious specificity, so the diagnosis is difficult and the misdiagnosis rate is high. Cardiac color ultrasound, chest CT and cardiac MR imaging examinations are of great significance for the diagnosis of this disease, but the final diagnosis requires histopathological examination. For the treatment of this disease, we can only get relevant treatment experience through case re-
ports at present. Individualized and comprehensive treatment such as surgery, chemotherapy and radiotherapy may improve the quality of life and prolong the survival time of patients, but there is still a lack of a large number of experimental supports, and the overall prognosis is very poor. This article reviews the latest research progress in the diagnosis and treatment of primary malignant pericardial mesothelioma in recent years, in order to provide reference for the clinical diagnosis and treatment of this disease.

Spinal muscular atrophy is a rare neuromuscular system disease with autosomal recessive inheritance, char-acterized by progressive myasthenia and muscular atrophy. With the development of neuroscience, many researches have en-riched the cognition of its diagnosis and treatment, providing a scientific and technological basis for tackling such rare diseasesin the future. This article reviews the clinical understanding and treatment progress of spinal muscular atrophy.

The knee joint is the largest and most complex joint of the human body. Degeneration and injury of the knee joint are common diseases in the middle-aged and elderly. Deep learning is developing rapidly in the medical field. This article reviews the research progress of deep learning in the MRI diagnosis of early knee osteoarthritis.