Report the clinical data of a patient with lysinuric protein intolerance with hemophagocytic syndrome, and review the literature.

Solid organ transplantation is the most effective treatment for end-stage organ failure. However, post-transplant rejection can damage the transplanted organ and reduce the survival time of the transplant. In recent years, liquid biopsy has become an important means for detecting and diagnosing rejection reactions, with particular attention paid to the study of exosomes. As biomarkers, exosomes have the advantages of being non-invasive and highly accurate in diagnosis, and can be used to diagnose transplant rejection.This article reviews the research progress of exosome detection in allogeneic organ transplant rejection, including kidneys, lungs, hearts, livers, etc.

Abnormal blood lipid levels can induce cancer cells to produce more cancer-promoting oxidized cholesterol, thus increasing the risk of gastric cancer. Lipoproteins are involved in the packaging, storage, transportation and metabolism of cells, and studies have found that their metabolism disorders may also be related to the risk of gastric cancer. This article reviews the research progress of serum lipid and lipoprotein levels and gastric cancer, in order to provide new ideas for the accurate treatment of gastric cancer, and provide a new direction for the study of the correlation between gastric cancer and lipid and lipoprotein.

Traditional Chinese medicine(TCM) has unique advantages in the treatment of tumor, and the use of TCM in clinical intervention of nasopharyngeal carcinoma has achieved remarkable curative effect. Apoptosis is a spontaneous programmed cell death process, which is closely related to the occurrence and development of tumors. Modern pharmacological studies have confirmed that a variety of TCM monomers and compounds can inhibit the development of nasopharyngeal carcinoma by inducing apoptosis, but the mechanism of inducing apoptosis of nasopharyngeal carcinoma cells has not been fully revealed due to the characteristics of TCM with multi-components, multi-pathways, multi-links and multi-targets. By searching, analyzing, summarizing and summarizing the relevant literatures at home and abroad in recent years, the author reviewed the mechanism of inducing apoptosis of nasopharyngeal carcinoma cells by TCM monomer and compound.

Abnormal glycolysis is a prominent feature of tumor cells, independent of oxygen availability. The metabolic pathway of tumor glycolysis has emerged as a significant focus in recent research on tumor mechanisms, diagnostics, and therapeutics. Gynecological malignancies exhibit high incidence and mortality rates, posing a significant threat to women's health and well-being. The heightened glycolytic capacity of these tumors is intricately linked to their biological behavior, response to radiotherapy and chemotherapy, treatment tolerance, malignant progression, and overall prognosis. Summarize the advancements in glycolysis metabolism research within major gynecological malignant tumors, offering novel insights for investigating mechanisms, diagnosing and treating these tumors, as well as evaluating prognosis.